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Postdoctoral Scholar - Research Associate

Quantitative and Computational Biology Los Angeles, California


The group of Dr. Adam L. MacLean at USC ( is recruiting a postdoctoral researcher  to work on mathematical and statistical models of stem cell lineage dynamics. We study fundamental questions regarding stem cell fate and its impact on disease using mathematical models, computational data analysis, and statistical inference. The candidate will develop new algorithms and models to describe cell state transitions in stem cell lineage systems. These build upon recent methods (Nucleic Acids Res, 2019, for the analysis and integration of single-cell data (RNA-seq, ATAC-seq, BS-seq, etc). The candidate will further develop multiscale models that integrate gene regulatory and cell lineage dynamics — informed by data-derived cell states — to test hypotheses and make predictions. They will develop methods to constrain models using Bayesian parameter inference and model selection. The candidate will lead interdisciplinary research projects working in close collaboration with experimental biologists, have the opportunity to mentor graduate and undergraduate students, and will be involved in every stage of the research process, from conceptualization to publication. Salary will follow or exceed NIH guidelines based on training and experience.

The MacLean Lab began in 2018 and is situated within Quantitative & Computational Biology: a vibrant and growing Research Section in the Dept. of Biological Sciences consisting of 10+ computational and theoretical biology labs.

We are dedicated to building a diverse and supportive research environment and especially encourage applications from underrepresented groups in science.

Requirements: • Applicants should hold (or expect to receive soon) a PhD in Computational Biology, Systems Biology, Applied Mathematics, Statistics, Computer Science, or a related subject. • Applicants should have experience in Python, R, Julia, or similar languages. • Applicants should have excellent writing and communication skills and enthusiasm for team science and collaboration. Location: USC University Park Campus, Los Angeles, California. Application: Informal enquiries should be submitted to When you are ready to apply, please submit your CV, a statement or research interests (no more than one page), and details of 2-3 referees. Applications received by May 15, 2019 will be given full consideration.

REQ20073071 Posted Date: 04/11/2019
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